The Coming Plague

Newly Emerging Diseases in a World Out of Balance

Laurie Garrett

15 min read
1m 14s intro

Brief summary

Human progress has inadvertently created ideal conditions for deadly microbes to emerge and spread globally. This book explains how our modern world, from megacities to antibiotic overuse, has made humanity more vulnerable to infectious diseases, shifting the fight from one of victory to one of constant preparedness.

Who it's for

This book is for anyone interested in public health, epidemiology, and how human civilization's expansion shapes the risk of pandemics.

The Coming Plague

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Why New Diseases Keep Appearing

In the early twentieth century, infectious disease shaped everyday life. Families expected to lose children to measles, whooping cough, scarlet fever, or tuberculosis. Doctors had fewer tools than they do today, but many were highly skilled at recognizing disease quickly because they saw so much of it. Then antibiotics and vaccines arrived, and for a time it seemed as if medicine had finally gained the upper hand.

That confidence did not last. By the late 1970s and early 1980s, one shock after another made it clear that the microbial world was still changing. Legionnaires’ disease appeared in the United States, Ebola erupted in central Africa, Lassa fever kept returning in West Africa, and AIDS emerged as a completely new global disaster. These were not old enemies in familiar form. They were warnings that microbes were still evolving and that human systems were not ready.

A deeper lesson began to emerge. Human activity was helping create the conditions for these outbreaks. Expanding cities, clearing forests, moving rapidly across continents, and crowding into poor urban settlements all gave microbes new chances to spread. Pathogens did not need evil intent. They only needed access to new hosts, and human societies were giving them that access again and again.

This changed the meaning of public health. Disease was no longer something that stayed in one village or one country. A virus in a forest edge, a slum, a refugee camp, or a hospital with poor sanitation could eventually reach any major city. The health of wealthy countries depended on the health of poor ones, whether politicians wanted to admit it or not.

At the same time, some of medicine’s old strengths were fading. Antibiotics were losing power, and many younger doctors had little experience recognizing dangerous infections before lab tests confirmed them. The central message was hard but clear: there would be no final victory over microbes. Survival would depend on constant attention, strong public health systems, and a better understanding of how human behavior reshapes the natural world.

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About the author

Laurie Garrett

Laurie Garrett is an American science journalist and author renowned for her expertise in global health, epidemics, and biosecurity. A former senior fellow for global health at the Council on Foreign Relations, she is the only journalist to have won the Pulitzer Prize, the Peabody Award, and the George Polk Award for her work covering infectious diseases and public health crises across the globe.

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