The Immortal Life of Henrietta Lacks

A narrative walkthrough of the book’s core ideas.

Rebecca Skloot

16 min read
1m 9s intro

Brief summary

In 1951, doctors took cancer cells from a Black tobacco farmer named Henrietta Lacks without her knowledge. Those cells, nicknamed HeLa, became the first 'immortal' human cell line, fueling a medical revolution while her family remained unaware for decades.

Who it's for

This book is for anyone interested in the intersection of medical ethics, racial history, and the human story behind scientific breakthroughs.

The Immortal Life of Henrietta Lacks

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Henrietta Lacks's Life Before Her Cancer Diagnosis

In January 1951, Henrietta Lacks, a thirty-year-old mother of five, walked into the segregated "colored" ward of Johns Hopkins Hospital with a "knot" in her womb. Born Loretta Pleasant in 1920, her life began in Roanoke, Virginia, but was shaped in the tobacco fields of Clover, where she was raised in a log cabin that had once been slave quarters. Life was a rhythm of tending livestock and stooping over tobacco plants, working alongside her cousin David "Day" Lacks, whom she married in 1941. Drawn by the promise of the Great Migration, the family left the red dirt of Virginia for the bustling Black community of Turner Station, Maryland, where Day found work at the Bethlehem Steel mill. It was here that Henrietta felt the ailment grow for over a year, but the demands of raising children and the barriers of Jim Crow medicine delayed her visit until she discovered a hard lump and began bleeding.

A physician found a shiny, purple tumor the size of a nickel on her cervix—a growth unlike any he had seen. A biopsy confirmed Stage I epidermoid carcinoma. At the same time, two prominent Hopkins researchers were on a collision course with Henrietta's fate. Dr. Richard TeLinde needed to grow living cancer cells to prove his theory that non-invasive carcinoma was a precursor to deadly invasive cancer. He partnered with Dr. George Gey, a researcher who had spent thirty years trying to create an "immortal" human cell line that could live and divide indefinitely outside the body. Gey’s lab, run with the sterile precision of his wife Margaret, was a place of hand-built innovation, functioning on a "witch’s brew" of chicken plasma and human umbilical cord blood, with samples kept in constant motion by a "whirligig" roller drum Gey had invented.

When Henrietta returned for her first radium treatment, the surgeon performed an unauthorized act. Before inserting the radioactive tubes, he shaved two dime-sized pieces of tissue from her cervix: one from the tumor and one from healthy tissue. Labeled simply "HeLa" (the first two letters of her first and last names), the samples were sent to Gey’s lab. There, his assistant Mary Kubicek followed a rigorous protocol, slicing the tissue and placing it in test tubes. While every previous human cell sample had perished, Henrietta’s cells did something unprecedented: they doubled every twenty-four hours, growing with a "mythological intensity." They became the first immortal human cell line, a breakthrough built on a foundation of silence. Henrietta was never told her tissue was taken, and for decades her family remained unaware that a part of her was still alive, fueling a revolution in medical science.

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About the author

Rebecca Skloot

Rebecca Skloot is an American science writer specializing in science and medicine, holding degrees in both biological sciences and creative nonfiction. Her work often takes a narrative approach to exploring the intersection of science, ethics, and daily life in articles for publications such as *The New York Times Magazine* and as a correspondent for programs like NPR's *Radiolab*. Skloot has also taught science journalism and creative writing at universities including New York University and the University of Pittsburgh.

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